RUSC1

Across TCGA cell cohorts, RUSC1 mutation is significantly associated with the mutation status of many other genes, with 4,362 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RUSC1-associated genes across cancer lineages are TICRR, GSE1, and SETD1A. Each is linked with RUSC1 in more than 4 cancer types. Because this analysis shows association rather than direction, both RUSC1-to-partner and partner-to-RUSC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TICRR grouped by RUSC1-low versus RUSC1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RUSC1→partner) and Y-score (partner→RUSC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TICRR →	+4.247	+4.554	.001	.001	1	5
PANCREAS	GSE1 →	+5.115	+5.115	.005	.005	1	4
PANCREAS	SETD1A →	+5.115	+5.115	.005	.005	1	4
SKIN	IPO11 →	+4.392	+4.392	.009	.009	1	4
BLOOD_Leukemia	FYCO1 →	+2.820	+3.080	.001	.001	1	4
BLOOD_Leukemia	ADAMTS15 →	+2.498	+2.847	.002	.002	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,362 associations by consensus.

TICRR by RUSC1 expression — BLOOD_Lymphoma

Explore this box plot interactively →