RUNX2-AS1

Across TCGA patient cohorts, RUNX2-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,034 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RUNX2-AS1-associated proteins across cancer lineages are MRC2, P3H1, and RUNX2_S28. Each is linked with RUNX2-AS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both RUNX2-AS1-to-partner and partner-to-RUNX2-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RUNX2-AS1 versus MRC2 in UCEC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RUNX2-AS1→partner) and Y-score (partner→RUNX2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MRC2 →	+0.594	+0.881	<.001	<.001	3	7
GBM	P3H1 →	+0.683	+0.604	<.001	<.001	3	7
LSCC	RUNX2_S28 →	+0.732	+0.589	<.001	<.001	3	6
UCEC	SH3PXD2B →	+0.356	+0.812	<.001	.001	3	6
PDAC	CRTAP →	+0.457	+0.500	<.001	<.001	3	6
LSCC	ITGB5 →	+0.532	+0.600	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,034 associations by consensus.

RUNX2-AS1 vs MRC2 — UCEC

Explore this scatter interactively →