RUNDC3B

Across TCGA cell cohorts, RUNDC3B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,580 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RUNDC3B-associated GO terms across cancer lineages are Gamma-aminobutyric acid signaling pathway, Presynaptic active zone organization, and Cytoplasmic translation. Each is linked with RUNDC3B in more than 6 cancer types. Because this analysis shows association rather than direction, both RUNDC3B-to-partner and partner-to-RUNDC3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Gamma-aminobutyric acid signaling pathway grouped by RUNDC3B-low versus RUNDC3B-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RUNDC3B→partner) and Y-score (partner→RUNDC3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Gamma-aminobutyric acid signaling pathway →	-0.169	-0.214	.003	.001	3	7
SKIN	Presynaptic active zone organization →	-0.139	-0.332	.001	.005	3	7
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translation →	+0.088	+0.317	.001	.001	3	7
UPPER_AERODIGESTIVE_TRACT	Regulation of postsynaptic membrane potential →	-0.150	-0.337	.003	<.001	3	7
BLOOD_Leukemia	Ribosomal subunit export from nucleus →	+0.072	+0.237	<.001	.006	3	6
SOFT_TISSUE	Monoatomic anion transport →	-0.055	-0.412	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,580 associations by consensus.

Gamma-aminobutyric acid signaling pathway by RUNDC3B expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →