RUNDC3B

Across TCGA cell cohorts, RUNDC3B mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RUNDC3B-associated genes across cancer lineages are F9, BANF2, and PLCZ1. Each is linked with RUNDC3B in more than 1 cancer types. Because this analysis shows association rather than direction, both RUNDC3B-to-partner and partner-to-RUNDC3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, F9 grouped by RUNDC3B-low versus RUNDC3B-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RUNDC3B→partner) and Y-score (partner→RUNDC3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	F9 →	+0.035	+4.523	<.001	.004	3	1
BLOOD_Lymphoma	BANF2 →	+0.071	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	PLCZ1 →	+0.114	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	LECT2 →	+0.899	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	RSPO1 →	+0.098	+4.191	<.001	.007	3	1
BLOOD_Lymphoma	GAGE12D →	+0.346	+4.643	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

F9 by RUNDC3B expression — BLOOD_Lymphoma

Explore this box plot interactively →