RUNDC3A-AS1

Across TCGA pan-cancer cohorts, RUNDC3A-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated RUNDC3A-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RUNDC3A-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RUNDC3A-AS1 expression acts as an unfavorable survival marker, although some lineages such as KICH and LGG show a favorable association.

KIRC, UVM, and UCEC are the cancer types where RUNDC3A-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.522	0.717	<.001	113	view →
UVM	DFS	Median	All	0.321	0.615	<.001	108	view →
UCEC	OS	Tertile	III,IV	0.434	0.762	.001	86	view →
COAD	OS	Quartile	All	0.670	0.883	<.001	73	view →
MESO	OS	Quartile	III,IV	0.333	0.725	<.001	58	view →
KICH	DFS	Tertile	III,IV	1.000	0.338	.005	53	view →
LGG	OS	Median	All	0.546	0.371	<.001	53	view →
LUAD	OS	Quartile	II,III,IV	0.834	0.594	.001	36	view →
UCS	DFS	Median	IV	0.367	0.952	.001	36	view →
LIHC	OS	Median	III,IV	0.222	0.467	.007	36	view →
CESC	OS	Median	IV	0.538	0.099	.022	30	view →
THYM	DFS	Median	All	0.788	1.000	<.001	29	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

RUNDC3A-AS1–KIRC (OS)

Open the KIRC breakdown →