RUNDC3A-AS1

Across TCGA pan-cancer cohorts, RUNDC3A-AS1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of RUNDC3A-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RUNDC3A-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types RUNDC3A-AS1 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

KIRC, THCA, and HNSC are the cancer types where RUNDC3A-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RUNDC3A-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	III,IV	−0.392	<.001	12	view →
THCA	Female	III,IV	+1.725	<.001	11	view →
HNSC	All	III,IV	+0.374	<.001	11	view →
LUAD	Female	III,IV	+1.065	<.001	9	view →
KICH	Female	All	+1.492	<.001	8	view →
LUSC	Male	II,III,IV	+0.716	<.001	6	view →
BRCA	All	III,IV	+0.659	<.001	6	view →
BLCA	All	All	+0.441	.002	6	view →
UCEC	All	All	+0.387	.009	4	view →
LIHC	All	All	+0.029	.001	4	view →
CHOL	All	All	+0.208	<.001	3	view →
KIRP	All	III,IV	+0.575	.011	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

RUNDC3A-AS1–KIRC

Open the KIRC breakdown →