Across TCGA patient cohorts, RUNDC1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RUNDC1-associated genes across cancer lineages are CD8+ naive T-cells, NKT, and Class-switched memory B-cells. Each is linked with RUNDC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RUNDC1-to-partner and partner-to-RUNDC1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RUNDC1→partner) and Y-score (partner→RUNDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ naive T-cells →	+0.059	+3.032	<.001	.018	3	2
SKCM	NKT →	+0.147	+3.176	.022	.010	1	1
UCEC	Class-switched memory B-cells →	-0.061	-3.321	.040	.010	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

RUNDC1 survival (RNA) · tumor vs normal (RNA) · all RUNDC1 data types