Across TCGA pan-cancer cohorts, RUNDC1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of RUNDC1’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where RUNDC1 RNA is repressed in tumor relative to normal tissue. In most cancer types RUNDC1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.
KICH, THCA, and LIHC are the cancer types where RUNDC1 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RUNDC1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.