Across TCGA cell cohorts, RUNDC1 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RUNDC1-associated genes across cancer lineages are MAGEB5, PIRT, and BTBD16. Each is linked with RUNDC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RUNDC1-to-partner and partner-to-RUNDC1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RUNDC1→partner) and Y-score (partner→RUNDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	MAGEB5 →	+0.033	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	PIRT →	+0.006	+4.643	<.001	.008	3	1
BLOOD_Leukemia	BTBD16 →	+0.105	+3.959	<.001	.005	3	1
BLOOD_Leukemia	MORN5 →	+0.305	+3.855	<.001	.007	3	1
UPPER_AERODIGESTIVE_TRACT	FABP9 →	+0.045	+4.357	<.001	.006	3	1
BLOOD_Lymphoma	AVP →	+0.031	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

RUNDC1 survival (RNA) · tumor vs normal (RNA) · all RUNDC1 data types