Across TCGA patient cohorts, RUFY2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,406 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RUFY2-associated genes across cancer lineages are VRK1, SCML2, and LMNB1. Each is linked with RUFY2 in more than 4 cancer types. Because this analysis shows association rather than direction, both RUFY2-to-partner and partner-to-RUFY2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RUFY2→partner) and Y-score (partner→RUFY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	VRK1 →	-0.772	-0.182	.002	.002	3	5
LSCC	SCML2 →	-1.018	-0.241	<.001	<.001	3	5
UCEC	LMNB1 →	-1.378	-0.425	<.001	<.001	3	5
BRCA	STMN1 →	-1.092	-0.296	<.001	<.001	3	5
BRCA	PIF1 →	-1.234	-0.274	<.001	<.001	3	5
LSCC	FANCI →	-0.702	-0.183	.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,406 associations by consensus.

Exploration

RUFY2 survival (RNA) · tumor vs normal (RNA) · all RUFY2 data types