Across TCGA patient cohorts, RUFY2 mutation is significantly associated with the RNA expression of many other genes, with 4,487 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RUFY2-associated genes across cancer lineages are ZNF92P1Y, RNY4P20, and RN7SL248P. Each is linked with RUFY2 in more than 2 cancer types. Because this analysis shows association rather than direction, both RUFY2-to-partner and partner-to-RUFY2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RUFY2→partner) and Y-score (partner→RUFY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	ZNF92P1Y →	+0.030	+6.589	<.001	<.001	3	3
LUAD	RNY4P20 →	+0.168	+4.155	.007	.007	3	3
LUAD	RN7SL248P →	+0.060	+4.000	<.001	.009	3	3
UCEC	CACYBP →	+0.553	+2.180	<.001	<.001	3	3
UCEC	BCL2A1 →	+0.606	+3.087	.003	<.001	3	3
UCEC	YTHDF3-AS1 →	+0.439	+1.939	.002	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,487 associations by consensus.

Exploration

RUFY2 survival (RNA) · tumor vs normal (RNA) · all RUFY2 data types