Across TCGA cell cohorts, RUFY2 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RUFY2-associated genes across cancer lineages are OR5H2, SLITRK3, and UGT2B4. Each is linked with RUFY2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RUFY2-to-partner and partner-to-RUFY2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RUFY2→partner) and Y-score (partner→RUFY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	OR5H2 →	+0.055	+4.321	<.001	.009	3	1
BLOOD_Leukemia	SLITRK3 →	+0.035	+3.874	<.001	.005	3	1
BLOOD_Leukemia	UGT2B4 →	+0.045	+3.855	.005	.007	3	1
BLOOD_Leukemia	TBPL2 →	+0.071	+4.044	.003	.004	3	1
BLOOD_Leukemia	FAM180A →	+0.056	+4.321	<.001	.002	3	1
LARGE_INTESTINE	PHOX2B →	+0.024	+3.658	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

RUFY2 survival (RNA) · tumor vs normal (RNA) · all RUFY2 data types