RUBCNL

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RUBCNL protein abundance is significantly associated with the RNA expression of many other genes, with 1,025 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RUBCNL-associated genes across cancer lineages are PF4V1, TSHZ3, and ROMO1. Each is linked with RUBCNL in more than 1 cancer types. Because this analysis shows association rather than direction, both RUBCNL-to-partner and partner-to-RUBCNL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RUBCNL versus PF4V1 in GBM, with a Pearson correlation of -0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RUBCNL→partner) and Y-score (partner→RUBCNL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMPF4V1 →-0.286-0.458.002.00931
GBMTSHZ3 →+0.931+0.610.002.00531
GBMROMO1 →-0.612-0.685.003.00631
GBMELL3 →-0.135-0.492<.001.00431
GBMZSWIM6 →+0.317+0.485.006.00531
GBMZNF428 →-0.544-0.472.005.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,025 associations by consensus.

RUBCNL vs PF4V1 — GBM

Per-sample scatter of RUBCNL vs PF4V1 in GBM (Pearson r = -0.58).

Explore this scatter interactively →

Exploration