RUBCNL

Across TCGA pan-cancer cohorts, RUBCNL RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated RUBCNL data layer compared with 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher RUBCNL RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RUBCNL expression acts as an unfavorable survival marker, although some lineages such as LUAD and HNSC show a favorable association.

LUAD, HNSC, and UCEC are the cancer types where RUBCNL RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	All	0.861	0.722	<.001	109	view →
HNSC	DFS	Median	All	0.666	0.536	<.001	99	view →
UCEC	DFS	Median	All	0.783	0.552	<.001	90	view →
LGG	DFS	Median	All	0.652	0.820	<.001	49	view →
KIRC	DFS	Median	IV	0.224	0.447	.003	32	view →
COAD	OS	Median	All	0.752	0.569	.001	26	view →
SKCM	OS	Tertile	IV	0.854	0.406	.002	24	view →
LIHC	OS	Tertile	III,IV	0.395	0.726	.003	18	view →
THCA	DFS	Quartile	All	0.927	0.535	.008	16	view →
UCS	OS	Median	All	0.570	0.782	.028	10	view →
LUSC	DFS	Median	II,III,IV	0.292	0.448	.018	9	view →
READ	OS	Median	All	0.975	0.824	.017	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

RUBCNL–LUAD (DFS)

Open the LUAD breakdown →