RUBCNL

Across TCGA patient cohorts, RUBCNL mutation is significantly associated with the RNA expression of many other genes, with 3,223 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RUBCNL-associated genes across cancer lineages are LINC02438, CARS1, and STAMBP. Each is linked with RUBCNL in more than 2 cancer types. Because this analysis shows association rather than direction, both RUBCNL-to-partner and partner-to-RUBCNL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02438 grouped by RUBCNL-low versus RUBCNL-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RUBCNL→partner) and Y-score (partner→RUBCNL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC02438 →	+0.741	+2.584	<.001	<.001	3	3
UCEC	CARS1 →	+0.500	+3.010	<.001	<.001	3	3
UCEC	STAMBP →	+0.338	+2.860	.004	.001	3	3
CESC	RNU6-1067P →	+0.456	+4.569	<.001	.005	3	2
CESC	CLK3P2 →	+0.183	+5.146	<.001	<.001	3	2
CESC	RNF19BPX →	+0.030	+6.174	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,223 associations by consensus.

LINC02438 by RUBCNL expression — UCEC

Explore this box plot interactively →