RTTN

Across TCGA patient cohorts, RTTN RNA expression is significantly associated with the protein abundance of many other proteins, with 13,798 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RTTN-associated proteins across cancer lineages are SMAD4, USO1, and PAF1. Each is linked with RTTN in more than 6 cancer types. Because this analysis shows association rather than direction, both RTTN-to-partner and partner-to-RTTN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RTTN versus SMAD4 in COAD, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RTTN→partner) and Y-score (partner→RTTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SMAD4 →	+0.331	+0.483	<.001	.001	3	7
LSCC	USO1 →	-0.239	-0.636	.004	<.001	3	6
COAD	PAF1 →	+0.264	+0.474	<.001	<.001	3	6
LSCC	RFC2 →	+0.516	+0.828	<.001	<.001	3	6
PDAC	MCM3 →	+0.634	+0.329	<.001	<.001	3	6
LUAD	MCM4 →	+0.612	+0.250	<.001	.009	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,798 associations by consensus.

RTTN vs SMAD4 — COAD

Explore this scatter interactively →