Across TCGA patient cohorts, RTP5 mutation is significantly associated with the RNA expression of many other genes, with 1,904 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RTP5-associated genes across cancer lineages are RNU6-1318P, RN7SL299P, and HMGB1P44. Each is linked with RTP5 in more than 2 cancer types. Because this analysis shows association rather than direction, both RTP5-to-partner and partner-to-RTP5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTP5→partner) and Y-score (partner→RTP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-1318P →	+0.107	+2.484	.005	.008	3	3
LGG	RN7SL299P →	+0.314	+5.936	<.001	.002	3	2
SKCM	HMGB1P44 →	+0.070	+2.072	<.001	.002	3	2
UCEC	TMEM269 →	+0.229	+2.534	<.001	.001	3	2
COAD	S100A13 →	+0.783	+3.335	.002	.005	3	2
UCEC	KIFBP →	+0.591	+2.534	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,904 associations by consensus.

Exploration

RTP5 survival (RNA) · tumor vs normal (RNA) · all RTP5 data types