RTP4

Across TCGA patient cohorts, RTP4 mutation is significantly associated with the RNA expression of many other genes, with 268 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RTP4-associated genes across cancer lineages are RNU6-440P, SNRPGP17, and RN7SL840P. Each is linked with RTP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both RTP4-to-partner and partner-to-RTP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-440P grouped by RTP4-low versus RTP4-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTP4→partner) and Y-score (partner→RTP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-440P →	+0.352	+7.640	<.001	.009	3	2
UCEC	SNRPGP17 →	+0.237	+2.071	.007	.005	3	1
UCEC	RN7SL840P →	+0.276	+2.262	.002	.003	3	1
UCEC	MIR8082 →	+0.414	+2.561	<.001	.003	3	1
UCEC	LINC00869 →	-0.674	-3.676	<.001	.001	3	1
BLCA	CCNYL3 →	+0.044	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 268 associations by consensus.

RNU6-440P by RTP4 expression — BLCA

Explore this box plot interactively →