RTP4

Across TCGA pan-cancer cohorts, RTP4 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated RTP4 data layer compared with 5 for mutation status and 2 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher RTP4 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RTP4 expression acts as an unfavorable survival marker, although some lineages such as MESO and BLCA show a favorable association.

MESO, BLCA, and SKCM are the cancer types where RTP4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	All	0.558	0.268	<.001	108	view →
BLCA	OS	Median	All	0.790	0.646	<.001	86	view →
SKCM	OS	Tertile	All	0.860	0.739	<.001	48	view →
THYM	DFS	Median	All	0.791	1.000	<.001	45	view →
LGG	OS	Tertile	All	0.359	0.534	<.001	43	view →
CESC	OS	Tertile	All	0.939	0.829	.007	38	view →
THCA	OS	Median	All	0.996	0.891	<.001	38	view →
LAML	DFS	Median	All	0.476	0.660	.002	30	view →
SARC	OS	Median	All	0.849	0.640	<.001	30	view →
PAAD	OS	Median	All	0.526	0.695	.002	25	view →
READ	DFS	Tertile	II,III,IV	0.748	0.318	.007	24	view →
KIRC	DFS	Median	All	0.854	0.732	.010	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

RTP4–MESO (OS)

Open the MESO breakdown →