RTN4R

Across TCGA patient cohorts, RTN4R protein abundance is significantly associated with the RNA expression of many other genes, with 3,534 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RTN4R-associated genes across cancer lineages are PDE6H, FUT9, and DPY19L2P5. Each is linked with RTN4R in more than 1 cancer types. Because this analysis shows association rather than direction, both RTN4R-to-partner and partner-to-RTN4R results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RTN4R versus PDE6H in OV, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTN4R→partner) and Y-score (partner→RTN4R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PDE6H →	+0.323	+0.591	.007	.007	3	2
GBM	FUT9 →	+0.829	+0.405	.002	.001	3	2
OV	DPY19L2P5 →	+0.510	+0.591	<.001	.007	3	2
GBM	NPM1P43 →	+0.436	+0.470	.001	.006	3	2
LSCC	LIN7B →	+0.861	+0.631	.004	.007	3	2
LSCC	FAM20A →	-1.014	-0.467	.003	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,534 associations by consensus.

RTN4R vs PDE6H — OV

Explore this scatter interactively →