RTN1

Across TCGA patient cohorts, RTN1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,094 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RTN1-associated genes across cancer lineages are TM6SF1, GAB3, and PRKCB. Each is linked with RTN1 in more than 9 cancer types. Because this analysis shows association rather than direction, both RTN1-to-partner and partner-to-RTN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RTN1 versus TM6SF1 in OV, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTN1→partner) and Y-score (partner→RTN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TM6SF1 →	+0.759	+0.585	<.001	<.001	3	10
HNSC	GAB3 →	+0.845	+0.447	<.001	<.001	3	10
OV	PRKCB →	+1.075	+0.664	<.001	.001	3	10
HNSC	ANKRD44 →	+0.966	+0.516	<.001	<.001	3	10
OV	CSF2RB →	+1.015	+0.453	<.001	<.001	3	9
OV	TLR8 →	+1.030	+0.518	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,094 associations by consensus.

RTN1 vs TM6SF1 — OV

Explore this scatter interactively →