RTN1

Across TCGA cell cohorts, RTN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,750 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible RTN1-associated GO terms across cancer lineages are Cytoplasmic translation, Negative regulation of syncytium formation by plasma membrane fusion, and Mitochondrial electron transport, cytochrome c to oxygen. Each is linked with RTN1 in more than 8 cancer types. Because this analysis shows association rather than direction, both RTN1-to-partner and partner-to-RTN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by RTN1-low versus RTN1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RTN1→partner) and Y-score (partner→RTN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translation →	+0.108	+0.650	<.001	.001	3	9
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.099	+0.516	.001	.001	3	9
BLOOD_Leukemia	Mitochondrial electron transport, cytochrome c to oxygen →	+0.052	+1.088	<.001	.004	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.089	+0.494	.001	.002	3	8
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.097	+0.516	.001	.001	2	9
UPPER_AERODIGESTIVE_TRACT	ATP synthesis coupled electron transport →	+0.093	+0.526	.007	.004	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,750 associations by consensus.

Cytoplasmic translation by RTN1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →