RTN1

Across TCGA cell cohorts, RTN1 mutation is significantly associated with the RNA expression of many other genes, with 101 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible RTN1-associated genes across cancer lineages are OR5H6, SLC32A1, and ZNF479. Each is linked with RTN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RTN1-to-partner and partner-to-RTN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5H6 grouped by RTN1-low versus RTN1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTN1→partner) and Y-score (partner→RTN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	OR5H6 →	+0.018	+4.981	<.001	.008	3	2
BLOOD_Leukemia	SLC32A1 →	+0.529	+3.901	.002	.006	3	2
LUNG_SCLC	ZNF479 →	+0.028	+3.523	<.001	.008	3	2
OESOPHAGUS	CHRNA6 →	+0.249	+3.584	<.001	.008	3	1
OESOPHAGUS	H2AP →	+0.364	+3.836	<.001	.004	3	1
OESOPHAGUS	MOG →	+0.034	+3.652	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 101 associations by consensus.

OR5H6 by RTN1 expression — CNS

Explore this box plot interactively →