RTL8C

Across TCGA cell cohorts, RTL8C RNA expression is significantly associated with the go_rna of many other GO terms, with 5,734 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RTL8C-associated GO terms across cancer lineages are Protein targeting to vacuole involved in autophagy, Positive regulation of supramolecular fiber organization, and Positive regulation of actin filament bundle assembly. Each is linked with RTL8C in more than 13 cancer types. Because this analysis shows association rather than direction, both RTL8C-to-partner and partner-to-RTL8C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein targeting to vacuole involved in autophagy grouped by RTL8C-low versus RTL8C-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RTL8C→partner) and Y-score (partner→RTL8C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein targeting to vacuole involved in autophagy →	+0.238	+1.419	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Positive regulation of supramolecular fiber organization →	+0.118	+1.535	.002	.005	3	13
LIVER	Positive regulation of actin filament bundle assembly →	+0.169	+1.413	<.001	.002	3	13
LUNG_NSCLC_LUSC	Regulation of plasminogen activation →	+0.301	+1.731	.001	<.001	3	13
LIVER	Protein lipidation →	+0.144	+1.596	.001	.002	3	13
LUNG_NSCLC_LUSC	Response to water →	+0.208	+2.447	.003	.008	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,734 associations by consensus.

Protein targeting to vacuole involved in autophagy by RTL8C expression — BONE

Explore this box plot interactively →