Across TCGA patient cohorts, RTL8B mutation is significantly associated with the RNA expression of many other genes, with 836 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RTL8B-associated genes across cancer lineages are MIR8088, OR6K3, and PSMA3P1. Each is linked with RTL8B in more than 1 cancer types. Because this analysis shows association rather than direction, both RTL8B-to-partner and partner-to-RTL8B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTL8B→partner) and Y-score (partner→RTL8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR8088 →	+0.431	+7.473	<.001	.007	3	2
UCEC	OR6K3 →	+0.054	+2.398	.009	.001	3	2
LUAD	PSMA3P1 →	+0.076	+3.821	.004	.007	3	2
LUAD	LINC01872 →	+0.053	+4.285	<.001	.003	3	2
BRCA	DEFB104A →	+0.192	+7.473	<.001	.007	3	2
BRCA	RNU6-1311P →	+0.752	+4.721	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 836 associations by consensus.

Exploration

RTL8B survival (RNA) · tumor vs normal (RNA) · all RTL8B data types