RTL5

Across TCGA patient cohorts, RTL5 protein abundance is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RTL5-associated genes across cancer lineages are PLCL1, MMP21, and MALT1. Each is linked with RTL5 in more than 1 cancer types. Because this analysis shows association rather than direction, both RTL5-to-partner and partner-to-RTL5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RTL5 versus PLCL1 in LSCC, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTL5→partner) and Y-score (partner→RTL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PLCL1 →	+0.698	+0.986	<.001	.009	3	1
LSCC	MMP21 →	+0.360	+0.577	.005	.009	3	1
LSCC	MALT1 →	+1.004	+0.986	.006	.009	3	1
LSCC	CALHM5 →	+0.917	+0.986	<.001	.009	3	1
LSCC	RNU6-697P →	+1.725	+1.023	.005	.008	3	1
LSCC	KRTAP1-3 →	+0.324	+1.429	.006	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

RTL5 vs PLCL1 — LSCC

Explore this scatter interactively →