Across TCGA patient cohorts, RTL10 mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RTL10-associated genes across cancer lineages are FoxM1, A-Raf_pS299, and Gab2. Each is linked with RTL10 in more than 1 cancer types. Because this analysis shows association rather than direction, both RTL10-to-partner and partner-to-RTL10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTL10→partner) and Y-score (partner→RTL10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.263	+2.459	.035	.020	3	2
UCEC	A-Raf_pS299 →	-0.144	-3.000	.012	.036	3	1
UCEC	Gab2 →	+0.391	+2.459	.023	.020	3	1
UCEC	P-Cadherin →	-0.154	-2.446	.027	.020	3	1
UCEC	Annexin-1 →	+0.802	+3.189	.001	.010	3	1
UCEC	TFRC →	+0.536	+2.459	.036	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

RTL10 survival (RNA) · tumor vs normal (RNA) · all RTL10 data types