Across TCGA pan-cancer cohorts, RTL10 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated RTL10 data layer compared with 4 for mutation status and 2 for mass-spec protein.
The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RTL10 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RTL10 expression acts as an unfavorable survival marker, although some lineages such as HNSC and THYM show a favorable association.
ACC, LIHC, and HNSC are the cancer types where RTL10 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.