RTL1

Across TCGA cell cohorts, RTL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 794 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RTL1-associated GO terms across cancer lineages are Regulation of RNA splicing, Regulation of transferase activity, and Regulation of mRNA processing. Each is linked with RTL1 in more than 4 cancer types. Because this analysis shows association rather than direction, both RTL1-to-partner and partner-to-RTL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of RNA splicing grouped by RTL1-low versus RTL1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RTL1→partner) and Y-score (partner→RTL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of RNA splicing →	+0.036	+0.149	.005	.009	3	5
BLOOD_Leukemia	Regulation of transferase activity →	+0.026	+0.091	<.001	.003	3	5
LARGE_INTESTINE	Regulation of mRNA processing →	+0.055	+0.007	<.001	.005	3	4
BLOOD_Leukemia	Regulation of cell-substrate junction organization →	+0.036	+0.090	.007	.003	3	4
BLOOD_Leukemia	Negative regulation of myoblast fusion →	+0.051	+0.125	<.001	.005	3	4
BLOOD_Leukemia	Negative regulation of amyloid-beta formation →	+0.075	+0.136	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 794 associations by consensus.

Regulation of RNA splicing by RTL1 expression — BLOOD_Leukemia

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