RTF2

Across TCGA patient cohorts, RTF2 mutation is significantly associated with the RNA expression of many other genes, with 2,865 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RTF2-associated genes across cancer lineages are RNA5SP411, LINC02366, and RNU6-741P. Each is linked with RTF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RTF2-to-partner and partner-to-RTF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP411 grouped by RTF2-low versus RTF2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTF2→partner) and Y-score (partner→RTF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP411 →	+1.492	+2.616	<.001	<.001	3	2
BRCA	LINC02366 →	+0.074	+5.506	<.001	.005	3	2
UCEC	RNU6-741P →	+0.234	+3.306	<.001	.003	3	2
UCEC	RNU6-554P →	+0.395	+1.532	<.001	.007	3	2
UCEC	RNU2-14P →	+0.245	+2.063	<.001	.009	3	2
UCEC	PAICSP7 →	+0.076	+2.116	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,865 associations by consensus.

RNA5SP411 by RTF2 expression — UCEC

Explore this box plot interactively →