RSPH6A

Across TCGA patient cohorts, RSPH6A mutation is significantly associated with the RNA expression of many other genes, with 1,339 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RSPH6A-associated genes across cancer lineages are CENPU, ABHD3, and AZI2. Each is linked with RSPH6A in more than 2 cancer types. Because this analysis shows association rather than direction, both RSPH6A-to-partner and partner-to-RSPH6A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CENPU grouped by RSPH6A-low versus RSPH6A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSPH6A→partner) and Y-score (partner→RSPH6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CENPU →	+0.641	+3.628	.004	.001	3	3
UCEC	ABHD3 →	+0.714	+2.354	<.001	.003	3	3
UCEC	AZI2 →	+0.424	+2.156	.008	.009	3	3
UCEC	MAP2K1 →	+0.511	+2.254	.002	.005	3	3
UCEC	AAGAB →	+0.458	+2.815	.002	.001	3	3
UCEC	ARPP19 →	+0.506	+3.513	.002	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,339 associations by consensus.

CENPU by RSPH6A expression — UCEC

Explore this box plot interactively →