RSPH6A

Across TCGA cell cohorts, RSPH6A mutation is significantly associated with the RNA expression of many other genes, with 771 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RSPH6A-associated genes across cancer lineages are RNASE9, TFIP11, and ANKRD54. Each is linked with RSPH6A in more than 1 cancer types. Because this analysis shows association rather than direction, both RSPH6A-to-partner and partner-to-RSPH6A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNASE9 grouped by RSPH6A-low versus RSPH6A-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSPH6A→partner) and Y-score (partner→RSPH6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	RNASE9 →	+0.009	+4.415	<.001	.007	3	1
LARGE_INTESTINE	TFIP11 →	+0.411	+2.502	.003	.005	3	1
LARGE_INTESTINE	ANKRD54 →	+0.498	+2.588	.001	.004	3	1
LARGE_INTESTINE	MIOX →	+0.260	+2.502	.001	.005	3	1
LARGE_INTESTINE	RPL3 →	+0.440	+3.067	.007	.009	3	1
LARGE_INTESTINE	EIF3D →	+0.504	+3.628	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 771 associations by consensus.

RNASE9 by RSPH6A expression — SKIN

Explore this box plot interactively →