RSPH4A

Across TCGA cell cohorts, RSPH4A mutation is significantly associated with the RNA expression of many other genes, with 929 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RSPH4A-associated genes across cancer lineages are FIGLA, ACSM2A, and SUPT20HL1. Each is linked with RSPH4A in more than 1 cancer types. Because this analysis shows association rather than direction, both RSPH4A-to-partner and partner-to-RSPH4A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FIGLA grouped by RSPH4A-low versus RSPH4A-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSPH4A→partner) and Y-score (partner→RSPH4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	FIGLA →	+0.130	+4.029	.001	.009	3	1
OVARY	ACSM2A →	+0.045	+4.029	.006	.009	3	1
OVARY	SUPT20HL1 →	+0.092	+4.807	<.001	.003	3	1
LUNG_NSCLC_LUAD	TDRD15 →	+0.351	+5.149	<.001	<.001	3	1
LUNG_NSCLC_LUAD	OR8B4 →	+0.032	+4.472	<.001	.001	3	1
LARGE_INTESTINE	GGA1 →	+0.492	+2.158	.009	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 929 associations by consensus.

FIGLA by RSPH4A expression — OVARY

Explore this box plot interactively →