RSPH1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RSPH1 mutation is significantly associated with the RNA expression of many other genes, with 2,064 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RSPH1-associated genes across cancer lineages are LINC02103, SOCS7, and PAICSP2. Each is linked with RSPH1 in more than 2 cancer types. Because this analysis shows association rather than direction, both RSPH1-to-partner and partner-to-RSPH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02103 grouped by RSPH1-low versus RSPH1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSPH1→partner) and Y-score (partner→RSPH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCLINC02103 →+0.764+5.355<.001.00533
UCECSOCS7 →+0.555+3.592.009.00132
LIHCPAICSP2 →+0.043+5.268<.001.00632
LIHCNICN2P →+0.120+5.186<.001.00732
UCECRNU6-120P →+0.254+3.008<.001.00732
SKCMRNU6-218P →+0.386+2.609<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,064 associations by consensus.

LINC02103 by RSPH1 expression — LIHC

Box plot of LINC02103 in RSPH1-low vs RSPH1-high samples in LIHC.

Explore this box plot interactively →

Exploration