Across TCGA pan-cancer cohorts, RSL24D1P4 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RSL24D1P4’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where RSL24D1P4 RNA is repressed in tumor relative to normal tissue. In most cancer types RSL24D1P4 is over-expressed in tumor, although a few such as STAD show the opposite, repressed pattern.
STAD and HNSC are the cancer types where RSL24D1P4 tumor–normal differential expression is most reproducible.