RSL1D1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RSL1D1 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RSL1D1-associated genes across cancer lineages are Astrocytes, MPP, and aDC. Each is linked with RSL1D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RSL1D1-to-partner and partner-to-RSL1D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Astrocytes grouped by RSL1D1-low versus RSL1D1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSL1D1→partner) and Y-score (partner→RSL1D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADAstrocytes →+0.040+2.692.048.04831
STADMPP →+0.034+2.809<.001.04031
UCECaDC →+0.072+2.233.020.00631
UCEClymphatic Endothelial cells →-0.021-3.544.033.00231
UCECpDC →+0.047+1.711.021.02711
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Astrocytes by RSL1D1 expression — COAD

Box plot of Astrocytes in RSL1D1-low vs RSL1D1-high samples in COAD.

Explore this box plot interactively →

Exploration