RSL1D1

Across TCGA cell cohorts, RSL1D1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RSL1D1-associated genes across cancer lineages are HIGD1C, HHLA1, and MCHR2. Each is linked with RSL1D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RSL1D1-to-partner and partner-to-RSL1D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HIGD1C grouped by RSL1D1-low versus RSL1D1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSL1D1→partner) and Y-score (partner→RSL1D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	HIGD1C →	+0.063	+4.662	<.001	.005	3	1
BLOOD_Leukemia	HHLA1 →	+0.011	+4.551	<.001	.004	3	1
BLOOD_Leukemia	MCHR2 →	+0.034	+4.539	<.001	.007	3	1
BLOOD_Leukemia	TSSK1B →	+0.019	+4.874	<.001	.002	3	1
BLOOD_Leukemia	OR1D4 →	+0.046	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

HIGD1C by RSL1D1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →