RSF1-IT2

Across TCGA pan-cancer cohorts, RSF1-IT2 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated RSF1-IT2 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RSF1-IT2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RSF1-IT2 expression acts as an unfavorable survival marker, although some lineages such as STAD and LUSC show a favorable association.

UCEC, KIRC, and ACC are the cancer types where RSF1-IT2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	II,III,IV	0.670	0.862	.002	84	view →
KIRC	OS	Median	All	0.572	0.732	.001	80	view →
ACC	DFS	Median	All	0.270	0.631	<.001	68	view →
STAD	OS	Quartile	All	0.654	0.425	.004	48	view →
BLCA	OS	Quartile	III,IV	0.378	0.688	.013	16	view →
LUSC	DFS	Tertile	II,III,IV	0.552	0.317	.017	15	view →
READ	OS	Quartile	All	0.840	1.000	.013	11	view →
CESC	DFS	Tertile	All	0.654	0.482	.013	10	view →
LIHC	OS	Median	III,IV	0.316	0.642	.020	9	view →
SKCM	DFS	Median	III,IV	0.168	0.441	.005	8	view →
UVM	DFS	Quartile	III,IV	0.310	0.627	.026	4	view →
PAAD	OS	Median	III,IV	0.629	1.000	.022	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

RSF1-IT2–UCEC (OS)

Open the UCEC breakdown →