RSF1-IT2

Across TCGA pan-cancer cohorts, RSF1-IT2 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of RSF1-IT2’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where RSF1-IT2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RSF1-IT2 is over-expressed in tumor.

STAD, HNSC, and CHOL are the cancer types where RSF1-IT2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RSF1-IT2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	II,III,IV	+0.271	.005	7	view →
HNSC	Male	All	+0.233	.001	7	view →
CHOL	Male	All	+0.283	.008	3	view →
THCA	Male	All	+0.204	.009	2	view →
LUAD	Male	III,IV	+0.411	.045	1	view →
LUSC	Female	III,IV	+0.320	.003	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

RSF1-IT2–STAD

Open the STAD breakdown →