RSF1-IT1

Across TCGA pan-cancer cohorts, RSF1-IT1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated RSF1-IT1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RSF1-IT1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RSF1-IT1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and LUAD show a favorable association.

UVM, UCEC, and ACC are the cancer types where RSF1-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	III,IV	0.300	0.829	<.001	93	view →
UCEC	DFS	Median	All	0.510	0.785	<.001	70	view →
ACC	DFS	Median	All	0.146	0.718	<.001	57	view →
KICH	DFS	Quartile	II,III,IV	0.605	1.000	.002	44	view →
CHOL	DFS	Tertile	II,III,IV	0.120	0.634	<.001	36	view →
ESCA	OS	Tertile	III,IV	0.563	0.293	.008	18	view →
LUAD	DFS	Median	IV	0.777	0.212	.001	18	view →
MESO	DFS	Median	IV	0.572	0.192	.001	15	view →
SKCM	OS	Tertile	IV	0.335	0.752	.001	12	view →
COAD	OS	Tertile	All	0.551	0.717	.017	11	view →
KIRC	DFS	Tertile	All	0.762	0.847	.023	10	view →
PAAD	DFS	Tertile	All	0.203	0.408	.029	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

RSF1-IT1–UVM (OS)

Open the UVM breakdown →