RSF1-IT1

Across TCGA pan-cancer cohorts, RSF1-IT1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RSF1-IT1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where RSF1-IT1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RSF1-IT1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

BLCA, STAD, and BRCA are the cancer types where RSF1-IT1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RSF1-IT1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Female	III,IV	+0.122	.004	8	view →
STAD	All	II,III,IV	+0.204	.002	6	view →
BRCA	All	All	+0.251	<.001	4	view →
LUAD	All	All	+0.295	.008	2	view →
ESCA	Female	All	+0.303	.001	1	view →
COAD	All	All	+0.123	.049	1	view →
THCA	All	II,III,IV	−0.103	.012	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

RSF1-IT1–BLCA

Open the BLCA breakdown →