RSC1A1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RSC1A1 mutation is significantly associated with the RNA expression of many other genes, with 3,401 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RSC1A1-associated genes across cancer lineages are RNA5SP407, RNA5SP408, and MIR588. Each is linked with RSC1A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both RSC1A1-to-partner and partner-to-RSC1A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSC1A1→partner) and Y-score (partner→RSC1A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCRNA5SP407 →+0.517+7.924<.001<.00133
LUSCRNA5SP408 →+1.013+6.918<.001<.00133
LUADMIR588 →+0.529+5.631<.001.00432
LUSCRNU6-468P →+0.443+4.978<.001.00532
LUSCRNA5SP419 →+1.034+6.102<.001.00132
LUSCRNA5SP418 →+0.995+6.563<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,401 associations by consensus.

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