Across TCGA patient cohorts, RSC1A1 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RSC1A1-associated genes across cancer lineages are eEF2, FOXO3a, and GSK-3a-b_pS21_S9. Each is linked with RSC1A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RSC1A1-to-partner and partner-to-RSC1A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSC1A1→partner) and Y-score (partner→RSC1A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.372	+2.000	.021	.032	3	1
UCEC	FOXO3a →	-0.092	-2.292	.044	.034	3	1
UCEC	GSK-3a-b_pS21_S9 →	+0.442	+2.179	.021	.034	3	1
UCEC	JNK_pT183_Y185 →	-0.243	-2.687	.001	.006	3	1
UCEC	JNK2 →	+0.354	+3.331	<.001	.005	3	1
UCEC	Ku80 →	+0.343	+3.469	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Exploration

RSC1A1 survival (RNA) · tumor vs normal (RNA) · all RSC1A1 data types