RSBN1L

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RSBN1L mutation is significantly associated with the RNA expression of many other genes, with 2,359 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RSBN1L-associated genes across cancer lineages are RNU6-940P, MRPS15P1, and ANKRD20A6P. Each is linked with RSBN1L in more than 2 cancer types. Because this analysis shows association rather than direction, both RSBN1L-to-partner and partner-to-RSBN1L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSBN1L→partner) and Y-score (partner→RSBN1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
READRNU6-940P →+0.280+5.096<.001.00233
READMRPS15P1 →+0.082+3.827.001.00632
READANKRD20A6P →+0.152+4.341<.001.00732
CESCAIDAP3 →+0.050+5.812<.001.00332
COADRPL9P6 →+0.385+5.435<.001.00532
COADRPL23AP56 →+0.193+6.392<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,359 associations by consensus.

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