RSBN1

Across TCGA cell cohorts, RSBN1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RSBN1-associated genes across cancer lineages are WDR87, AVP, and ETDC. Each is linked with RSBN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RSBN1-to-partner and partner-to-RSBN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WDR87 grouped by RSBN1-low versus RSBN1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSBN1→partner) and Y-score (partner→RSBN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	WDR87 →	+0.028	+4.095	<.001	.009	3	2
BLOOD_Lymphoma	AVP →	+0.031	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	ETDC →	+0.556	+5.209	<.001	.005	3	1
LUNG_NSCLC_LUAD	KHDC3L →	+0.027	+3.215	<.001	.007	3	1
SKIN	BNIP5 →	+0.045	+4.523	<.001	.003	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

WDR87 by RSBN1 expression — SKIN

Explore this box plot interactively →