RSAD2

Across TCGA patient cohorts, RSAD2 mutation is significantly associated with the RNA expression of many other genes, with 2,067 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RSAD2-associated genes across cancer lineages are TRBV11-3, DNAJA3, and TMEM186. Each is linked with RSAD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RSAD2-to-partner and partner-to-RSAD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRBV11-3 grouped by RSAD2-low versus RSAD2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSAD2→partner) and Y-score (partner→RSAD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TRBV11-3 →	+0.555	+3.627	<.001	.008	3	2
UCEC	DNAJA3 →	+0.600	+3.080	<.001	<.001	3	2
UCEC	TMEM186 →	+0.489	+3.201	.003	.009	3	2
UCEC	TMLHE →	+0.485	+3.483	.005	.002	3	2
UCEC	ZBTB6 →	+0.523	+3.815	.005	<.001	3	2
UCEC	LINC02528 →	+0.274	+2.681	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,067 associations by consensus.

TRBV11-3 by RSAD2 expression — COAD

Explore this box plot interactively →