RSAD2

Across TCGA patient cohorts, RSAD2 mutation is significantly associated with the total protein of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RSAD2-associated genes across cancer lineages are Notch1, Cyclin-B1, and eEF2K. Each is linked with RSAD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RSAD2-to-partner and partner-to-RSAD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by RSAD2-low versus RSAD2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSAD2→partner) and Y-score (partner→RSAD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.222	+2.331	<.001	.019	3	2
UCEC	Cyclin-B1 →	+0.807	+3.321	.001	.010	3	2
LUSC	eEF2K →	+0.414	+2.816	.029	.036	3	1
UCEC	EGFR_pY1068 →	-0.356	-3.584	.001	.002	2	2
UCEC	EGFR →	-0.213	-2.321	.003	.034	3	1
UCEC	A-Raf_pS299 →	-0.187	-3.321	<.001	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

Notch1 by RSAD2 expression — UCEC

Explore this box plot interactively →