RS1

Across TCGA patient cohorts, RS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,300 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RS1-associated proteins across cancer lineages are VEPH1_S430, SEC63_T537, and SEPTIN4_S118. Each is linked with RS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both RS1-to-partner and partner-to-RS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RS1 versus VEPH1_S430 in GBM, with a Pearson correlation of 0.16.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RS1→partner) and Y-score (partner→RS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	VEPH1_S430 →	+1.150	+0.109	.005	.003	3	3
CCRCC	SEC63_T537 →	-0.980	-0.128	<.001	<.001	3	3
LSCC	SEPTIN4_S118 →	+0.689	+0.166	<.001	<.001	3	3
LSCC	LZTS2_S301 →	-0.627	-0.183	<.001	.002	3	3
CCRCC	PCF11_S511 →	-0.495	-0.110	<.001	.003	3	3
CCRCC	PHKA1_S758 →	-0.718	-0.082	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,300 associations by consensus.

RS1 vs VEPH1_S430 — GBM

Explore this scatter interactively →