RRP9

Across TCGA patient cohorts, RRP9 mutation is significantly associated with the RNA expression of many other genes, with 1,083 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RRP9-associated genes across cancer lineages are LINC02563, RNU6-952P, and C5orf22. Each is linked with RRP9 in more than 1 cancer types. Because this analysis shows association rather than direction, both RRP9-to-partner and partner-to-RRP9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02563 grouped by RRP9-low versus RRP9-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RRP9→partner) and Y-score (partner→RRP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC02563 →	+0.872	+6.342	<.001	.001	3	2
BLCA	RNU6-952P →	+0.251	+4.704	<.001	.005	3	2
UCEC	C5orf22 →	+0.550	+3.343	.005	.005	3	2
UCEC	NUP50 →	+0.501	+3.000	.001	.001	3	2
SKCM	DNM1P17 →	+0.094	+2.721	.003	.002	3	2
UCEC	MIR615 →	+0.314	+2.717	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,083 associations by consensus.

LINC02563 by RRP9 expression — CESC

Explore this box plot interactively →