RRP9

Across TCGA pan-cancer cohorts, RRP9 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated RRP9 data layer compared with 2 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher RRP9 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RRP9 expression acts as an unfavorable survival marker, although some lineages such as UVM and SCLC show a favorable association.

LIHC, UVM, and ACC are the cancer types where RRP9 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Median	All	0.453	0.623	<.001	113	view →
UVM	DFS	Tertile	II,III,IV	0.787	0.380	<.001	102	view →
ACC	DFS	Median	All	0.185	0.714	<.001	96	view →
KIRC	DFS	Median	II,III,IV	0.715	0.880	<.001	90	view →
SCLC	OS	Median	II,III,IV	0.852	0.524	.001	50	view →
SARC	OS	Median	All	0.394	0.631	<.001	30	view →
PRAD	DFS	Quartile	All	0.861	0.952	.003	28	view →
READ	OS	Median	II,III,IV	1.000	0.820	.010	23	view →
CHOL	OS	Median	II,III,IV	0.892	0.439	.020	20	view →
THYM	DFS	Quartile	All	1.000	0.668	.006	19	view →
SKCM	DFS	Quartile	III,IV	0.159	0.511	.008	18	view →
ESCA	OS	Tertile	IV	0.856	0.219	.024	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

RRP9–LIHC (DFS)

Open the LIHC breakdown →